- Sepsis : Exo-Target® loaded with anti-inflammatory protein which is delivered intra-cellularly into target cells (i.e. innate immune cells) to specifically inhibit sepsis causing inflammatory signaling pathway.
- Preterm Birth : Exo-Target® can deliver anti-inflammatory protein through placenta barrier to control pre-term inflammation in the placenta which is the main cause of preterm labor of pregnant woman.
Inborn Errors of Metabolism
- Gaucher’s Disease : In the metabolic disease, Exo-Target® can deliver the enzyme to the target cells in the liver and spleen for Type 1 Gaucher’s Disease (GD1) treatment. Exo-Target® can also across BBB for API delivery to the neuronal cells for Type 2 & 3 Gaucher’s Disease (GD2 and 3) treatment.
Our therapeutic exosomes, Exo-Target®, have high potential to be applied for
infinite pipelines depending on cargo proteins and targeting mechanisms.